BME 7900 Seminar - Jana Kainerstorfer, PhD - ZOOM SEMINAR

Description

For our next guest speaker, we welcome Dr. Jana Kainerstorfer from Carnegie Mellon University, where she is an Assistant Professor of Biomedical Engineering. She also holds courtesy appointments in Center for the Neural Basis of Cognition and Electrical & Computer Engineering. Development of Optical Imaging Methods to Assess Cerebral Perfusion at the Bedside Abstract: Bedside monitoring of cerebral perfusion is important for a variety of diseases, including traumatic brain injury, hydrocephalus, sepsis, and stroke, where inadequate perfusion can lead to ischemia and neuronal damage. Perfusion changes are driven by intracranial pressure (ICP), which is typically measured by invasive probes placed in the brain. We have developed non-invasive alternatives to measure ICP, which are based on measuring cerebral perfusion. For this we developed an animal model of hydrocephalus and measured cerebral hemodynamics with optical techniques, such as near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS). This talk will summarize our optical imaging methods, experimental procedures, and results as well as the path towards clinical translation. Bio: Dr. Kainerstorfer's research is focused on developing noninvasive optical imaging methods for disease detection and/or treatment monitoring, with an emphasis on diffuse optical imaging. She serves on program committees for the SPIE Photonics West and the OSA Biophotonics Congress. She is an Associate Editor of IEEE Transactions on Biomedical Engineering (TBME) and is an editor for the OSA Virtual Journal of Biomedical Optics. Her work has been supported by the National Institutes of Health, the American Heart Association, the Pennsylvania Infrastructure Technology Alliance, and the Center for Machine Learning and Health.