BME7900 Seminar Series - Matthias Nahrendorf, MD, PhD

Description

We welcome our next speaker Dr. Matthias Nahrendorft from Harvard Medical School - MGH Research Institute. He is the Richard Moerschner Endowed Chair at the MGH Research Institute, and a Professor for Radiology at Harvard Medical School.

Myeloid Cells in Cardiovascular Health

Dr. Naharendofrt is a Principal Investigator at the MGH Center for Systems Biology and adjunct Professor of Medicine at the Julius-Maximilians-Universität Würzburg. He also directs the Mouse Imaging Program at MGH. His laboratory focuses on the role of immunity in cardiovascular disease, specifically in atherosclerosis and heart failure. The lab described that after myocardial infarction, increased sympathetic nerve activity modulates the hematopoietic stem cell niche, activating migration and proliferation of myeloid progenitor cells. This, in turn, accelerated the progression of atherosclerosis (Nature 2012), possibly explaining why secondary infarcts are so common in patients. The laboratory develops and employs imaging approaches to sample biology non-invasively, using MR, nuclear, optical and hybrid imaging. Dr. Nahrendorf is an editorial board member of JACC, Circ Res, European Heart Journal, ATVB, Circulation, Science Translational Medicine, and The Journal of Nuclear Medicine. He was the Chair of the 2017 Atherosclerosis Gordon Conference and currently serves on the NHLBI board of external experts. He published >300 articles with an H-index of 103. Dr Nahrendorf received the MGH Research Scholar prize in 2014, the Basic Research Award of the German Society of Cardiology in 2015 and the MGH Martin Prize in 2019.