Yi Wang holds the Faculty Distinguished Professorship at the Department of Radiology, and is a tenured Professor of Physics in Radiology, Professor of Biomedical Engineering, and the Principal Investigator of the 3T MRI facility at Cornell University. He studied theoretical physics and switched to applying physics in medicine. Prof. Wang has invented multiple MRI technologies that are very important to the clinical and scientific communities: i) the cardiac navigator method to compensate for motion artifacts that has been adapted by most major academic centers as a basic approach in cardiac MRI; ii) the time-resolved acquisition method to solve the critical problem of timing acquisition to contrast bolus arrival in clinical contrast enhanced MRA and the multiple-station stepping-table platform to offer high throughput imaging of various body parts; iii) the quantitative susceptibility mapping (QSM) method that has broken ground for a new field in MRI for studying tissue magnetism.
Prof Wang is interested in developing biomedical imaging methods using tools from computer science, electronic engineering, mathematics, and physics and using knowledge in biology, chemistry, life science and medicine. For the past decade, his group has been developing the Bayesian approach to optimally and systematically integrating various tools and knowledge to extract biologically or pathologically relevant information from imaging data. This has been leading to various technical innovations and developments including quantitative susceptibility mapping (QSM), superresolution 4D imaging in magnetic resonance imaging (MRI), multi-scale functional imaging - concurrent multi photon microscopy and MRI, and simultaneous neuromodulation and imaging. These technical innovations have helped biologists, clinicians, and life scientists improve capability of probing biological processes, accuracy of diagnosing diseases, and effectiveness of treating patients. As a principal investigator, Prof Wang has been leading various NIH projects on brain function, cancer, heart disease, multiple sclerosis, Parkinson's disease, stroke, and vascular diseases. Additional information can be found on his medical school website: http://weill.cornell.edu/mri/index.html
Principles of medical imaging, Magnetic Resonance Imaging (MRI)
- Wang, Yi, T Lui. 2014. "Decoding MRI Data for a Tissue Magnetic Biomarker Quantitative Susceptibility Mapping." Magn Reson Med.
- Kawaji, K., P. Spincemaille, T D. Nguyen, N. Thimmappa, M A. Cooper, M R. Prince, Yi Wang. 2013. "Direct Coronary Motion Extraction from a 2D Fat Image Navigator for Prospectively Gated Coronary MR Angiography." Magn Reson Med.
- Cooper, M A., T D. Nguyen, B. Xu, M R. Prince, M. Elad, Yi Wang, P Spincemaille. 2014. "Patch based reconstruction of undersampled data (PROUD) for high signal-to-noise ratio and high frame rate contrast enhanced liver imaging." Magn Reson Med.
- Dimov, A., T. Lui, P. Spincemaille, J S. Ecanow, H. Tan, R R. Edelman, Yi Wang. 2014. "Joint estimation of chemical shift and quantitative susceptibility mapping (chemical QSM).." Magn Reson Med.
- Zhang, J., T. Lui, A. Gupta, T. Nguyen, P. Spincemaille, Yi Wang. 2014. "Quantitative Mapping of Cerebral Metabolic Rate of Oxygen (CMRO2) using Quantitative Susceptibility Mapping (QSM).." Magn Reson Med.
Selected Awards and Honors
- Fellow of American Institute for Medical and Biological Engineering (AIMBE) 2006
- Fellow (International Society of Magnetic Resonance in Medicine) 2012
- Fellow (Institute of Electrical and Electronics Engineers) 2013
- Advanced Richard B. Mazess Scholarship (University of Wisconsin) 1993
- Graduate Fellowship (University of Wisconsin) 1988
- BS (Nuclear Physics), Fudan University, 1986
- MS (Theoretical Physics), University of Wisconsin, Milwaukee, 1988
- Ph D (Medical Physics), University of Wisconsin, Madison, 1994